Radical Cure: Inhibit a receptor to slow brain activity to normal levels.
Of 72 types of odour receptor on its antennae, at least 27 are tuned to detect chemicals found in perspiration.
Because scientists have found that having the gene for a certain dopamine receptor could predispose you to being influenced by the sight of other people drinking.
The researchers got the same high HDL levels results when they blocked the hypothalamus' melanocortin 4 receptor (MC4R) either by knocking it out or shutting it down with other chemicals.
CD 24並不具有胞質內結構域,但通過Siglec - g傳遞的信號就包括了一個免疫受體酪氨*相關抑制*基序immune receptor tyrosine - basedinhibitorymotif (ITIM)。
A particularly appealing one is the capsaicin receptor.
The study focused on different versions of a receptor for the neurotransmitter dopamine, which controls feelings of pleasure.
Moreover, low expression of the receptor was associated with greater risk of lymph node metastasis and high expression showed borderline association with lower tumor size.
Antagonists tend to be small molecules that bind irreversibly to the receptor preventing its normal function, while agonists may be small or large molecules (e.g. peptide or protein hormones).
The possibilities for manipulating the receptor do not end there.
The mutant receptor appears to have evolved long ago and to be widely dispersed.
HIV USES the CCR5 as a co-receptor (in addition to CD4 receptors) to latch on to and ultimately destroy immune system cells.
Many lines of physiological and pharmacological evidence show that AMPA receptor desensitization plays an important role in fast excitatory synaptic transmission by affecting transmission efficacy of individual synaptic bouton, integrative functions of neuron, and synapse plasticity.
Today many pharmaceutical companies are competing to develop capsaicin receptor antagonists.
In the brains of the treated mice, the researchers found changes in the activity of genes that encode portions of the receptor for the neurotransmiter GABA.
The stunted receptor does not pass the message on properly.
Eberhart and colleagues studied glioblastoma cell lines to investigate the effects of a gamma-secretase inhibitor, a medication that blocks the Notch receptor, on tumor growth.
This gene codes for a receptor - nicknamed a Toll-like receptor - that binds to a bacterial product involved in septic shock.
In the meantime, other scientists had identified a receptor in a group of neurons that enable fruit flies to smell carbon dioxide, which signals the presence of a good meal of tasty yeast.
In this review, we unraveled coding patterns of two olfactory systems for information recognition at three levels: olfactory receptor, olfactory bulb and higher brain region beyond the olfactory bulb.
macrophage scavenger receptor
Thus a receptor may be a protein, enzyme, membrane channel, or a region of a foreign pathogen.
This is most effective if a specific receptor blocking agent is available to counter the effects of a given agonist.