OBJECTIVE: To study chiral pharmacokinetics process of amlodipine enantiomers of rabbits in vivo.
Separation of enantiomers of fluorine-containing α-aminophosphonate by high performance liquid chromatography on the amylose chiral solid phase
The determination of R.S configuration of enantiomers;
Separation of ketoconazole enantiomers using high performance liquid chromatography with chiral mobile phase additives
" Racemate: Mixture of equal quantities of two enantiomers, substances whose molecular structures are mirror images of one another."
Methamphetamine exists as two enantiomers, dextrorotary and levorotary.
A gas chromatographic method was developed to directly determine the enantiomers of acrylic ketone alcohol and acrylic ketone acetate.
"The two enantiomers rotate polarized light through opposite angles, canceling each other out so that the racemic mixture has no optical activity. Racemization is the conversion of an optically active form of a compound into a racemic mixture; reversing this process is called resolution. "
First, amylose was selected as chiral selector and the enantiomeric separation of citalopram enantiomers was achieved successfully.
Direct chiral separation of naftopidil enantiomers by RP-HPLC using Chiralpak AD-RH
Resolution of sibutramine enantiomers with α_1-AGP chiral stationary phase
Direct resolution of citalopram enantiomers by chiral stationary phase using CHIRAEL OJ-H column
OBJECTIVE: to establish a pre column chiral derivatization reversed phase high performance liquid chromatographic method for the separation of ketoprofen enantiomers.
We also discuss effects of column temperature, the alcoholic modifier, additive and velocity of flow on the separation of the enantiomers.