CONCLUSION: Homocysteine can aggravate the injury of dopaminergic neurons in animal models of Parkinson disease, and the mechanism may be associated with the anti-oxidative stress.
To study the morphologic changes of dopaminergic neurons in VTA and SN in the dementia model group, control group and the old group, and to analyse the result concluded by image analysing system.
Time effect on differentiation of neural stem cells to dopaminergic neurons;
Parkinson's disease is characterized by the death of dopaminergic neurons in areas of the midbrain.