This "methylation" of GR appears to make the individual more tuned in or sensitised to stress, meaning that they will react to it quicker both mentally and hormonally.
Perhaps it's just me, but I'd swear the world knows not an eviler soul than an angry, angst-ridden, hormonally intoxicated teen.
Transsexuals alter their physical appearance cosmetically and hormonally, and may eventually undergo a sex-change operation.
Adrenal myelolipomas are benign, rare, and hormonally inactive tumors.