He was overtaken by misfortune.
It is not the law of the universe to remain unchanged, and if you are already happy, it is likely to be followed by misfortune.
"Little minds are tamed and subdued by misfortune, but great minds rise above them." - Washington Irving, Author.
Bo Ji was allowed to go to the feudal country of L Zi and honor the Empress Dowager because she was out of favor and was blessed by misfortune.
I found the slender young thing bent to the earth like an unfortunate creature borne down by misfortune.
Gentlemen, I can not be tolerated by such malice caused by misfortune.