Crossing fibers of the dorsal lemniscal system at the medulla that from the medial lemniscus .
The synaptic connections between the medial lemniscus and the thalamocortical projecting neurons (TPN) were studied by using both anterograde degenerating and HRP retrograde tracing methods.
At caudal hypo-thalamus level, it runs in ventral tegmental area and a region between medial lemniscus and cerebral peduncle.