The pathogenesis of postoperative pancreatitis is associated with direct injury to the pancreas, increase of the pancreatic enzyme secretion, block of the pancreatic ducts and disturbances of blood supply.
AP model was induced by retrograded injection of 4% sodium deoxycholate into the pancreatic duct.
Methods: Acute pancreatitis model was induced by intraperitoneal injection of cerulein or retrograde infusion of 5% sodium taurocholate into the bilipancreatic duct in SD rats.
Methods the effects of 5 FU were investigated in 8 patients who had undergone pancreatoduodenectomy. The pancreatic juice was temporarily diverted to the exterior via a pancreatic duct catheter.
The present study was done both in vivo by cannulating pancreatic duct of morphine dependent rats and in vitro using perfused pancreatic slices from morphine dependent rats.
In experienced hands, EUS-guided interventions may be capable of alleviating obstruction from the left hepatic biliary ducts or the pancreatic duct system, including rendezvous techniques with ERCP.
Conclusion the operation can disengage pancreatic duct obstruction, drain away the pancreatic fluid, prevent reflux and anastomotic leakage, is an effective treatment for pancreatic lithiasis.
Advances in imaging diagnosis of pancreatic duct abnormalities in pancreatic diseases
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