He's not as campy or flashy and doesn't use exotic animals.
And when I learned that GDI and NOD weren't actually in this game, it was discussed that it would be Allies and soviets, with a "what if" fun campy scenario.
From the black-and-white creepiness of early silent films to the campy kitsch of television series today, these bloodsuckers are so diffuse in popular culture that they might as well be real.